哺乳期妇女滴注广谱抗生素对孩子的影响

谢邀。这个确实可能受影响。不过,应该是暂时的,停了药会恢复。最好说清楚是哪一种头孢,可以针对性的查一下,不过大部分头孢都可以进入乳汁。建议是在哺乳妇女中慎用,也不是禁用,这种情况看医生拿捏了,如果母亲真的需要抗生素,紧密观察孩子,该用还是要用。As almost all drugs pass into milk from maternal plasma by passive diffusion, the M/P ratio is affected by the composition of the milk (aqueous, lipid, protein and pH) and the physicochemical characteristics of the drug (protein binding, lipophilicity and pKa). Milk contains substantially more lipid and less protein than plasma, and is slightly more acidic. Therefore, drugs which tend to concentrate in milk are weak bases, with low plasma protein binding and high lipid solubility.大部分药物是会进入母乳的。只是程度不同。跟药物本身的特性和母乳的特性有关。母乳中含有更多的脂肪和更少的蛋白质,并且略为酸性。所以弱碱性、脂溶性高和与蛋白质结合低的药物更容易进入母乳。一般来说,青霉素和头孢都算是安全的。进入母乳的剂量不大。主要的影响也就是改变肠道菌群了,在第三代头孢比较多见一些。一般来说这种抗生素也不会用太久。对以后应该是没有什么影响的,不用太担心。参考:http://www.australianprescriber.com/magazine/20/2/35/40


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