有哪些有意思的药品研发的故事( 二 )
《美国医学会-内科医学杂志》发表的批评氟班色林的文章六 尾声
一个或许并不存在的病和一个本不应该存在的药和在一起或许本身就是一个悲剧。当女权主义和资本主义的狂欢过后，“爱弟弟”，那个曾经被吹上殿堂的粉红色药片散落在床边阴暗的角落，无人问津，上面落满了一地鸡毛。
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参考资料与延伸阅读：
1， Borsini, Franco, et al. "Pharmacology of flibanserin." CNS Drug Reviews 8.2 (2002): 117-142.
2， Katz, Molly, et al. "Efficacy of flibanserin in women with hypoactive sexual desire disorder: results from the BEGONIA trial." The Journal of Sexual Medicine 10.7 (2013): 1807-1815.
3， DeRogatis, Leonard R., et al. "Treatment of hypoactive sexual desire disorder in premenopausal women: efficacy of flibanserin in the VIOLET Study." The Journal of Sexual Medicine 9.4 (2012): 1074-1085.
4， Thorp, John, et al. "Treatment of hypoactive sexual desire disorder in premenopausal women: efficacy of flibanserin in the DAISY study." The Journal of Sexual Medicine 9.3 (2012): 793-804.
5， Joffe, Hylton V., et al. "FDA approval of flibanserin—treating hypoactive sexual desire disorder." New England Journal of Medicine 374.2 (2016): 101-104.
6， Jaspers, Loes, et al. "Efficacy and safety of flibanserin for the treatment of hypoactive sexual desire disorder in women: a systematic review and meta-analysis." JAMA Internal Medicine176.4 (2016): 453-462.
7， Gellad, Walid F., Kathryn E. Flynn, and G. Caleb Alexander. "Evaluation of flibanserin: science and advocacy at the FDA." JAMA 314.9 (2015): 869-870.
8， Baid, Rashmi, and Rakesh Agarwal. "Flibanserin: A controversial drug for female hypoactive sexual desire disorder." Industrial Psychiatry Journal 27.1 (2018): 154.
9， https://www.thecut.com/2016/09/how-addyi-the-female-viagra-won-fda-approval.html
10， https://addyi.com/addyi/?utm_medium=cpc\u0026amp;utm_source=Google\u0026amp;utm_campaign=Addyi%20Brand%20Name\u0026amp;gclid=Cj0KCQjw1MXpBRDjARIsAHtdN-2p76p5C8SLN-hneMFKCM8iZLCiDRsi1OO1K_pQZCUlP_IqejFbVIEaAhZUEALw_wcB
11， https://www.bbc.com/ukchina/simp/vert_fut/2015/06/150612_vert_fut_female_viagra
12， https://www.mdedge.com/obgyn/article/100678/gynecology/flibanserin-poised-fda-approval-why-drug-and-why-now/page/0/1
13， https://en.wikipedia.org/wiki/Flibanserin
14， https://www.addyirems.com/AddyiUI/rems/pdf/prescribingInformation.pdf
15， Invernizzi, Roberto William, et al. "Flibanserin, a potential antidepressant drug, lowers 5‐HT and raises dopamine and noradrenaline in the rat prefrontal cortex dialysate: role of 5‐HT1A receptors." British Journal of Pharmacology 139.7 (2003): 1281-1288.
16， https://www.news-medical.net/news/20130627/Sprout-Pharmaceuticals-resubmits-flibanserin-NDA-for-treating-HSDD-in-pre-menopausal-women.aspx
17， https://www.npr.org/sections/health-shots/2015/06/04/411260331/advisers-to-fda-consider-controversial-drug-to-boost-female-libido
18， https://doi.org/10.1211%2FPJ.2015.20069201
19， https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/022526REMS.pdf
20， https://www.nytimes.com/2016/04/10/business/female-viagra-addyi-valeant-dysfunction.html?_r=1
【有哪些有意思的药品研发的故事】 21， https://en.wikipedia.org/wiki/Boehringer_Ingelheim
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